Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.65 |
| ▸ | PTGIR | P43119 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965139 | 0.87 | PTGDR2 (0.61) | PTGDR2PTGIRPTGDR | |
| SCHEMBL8804127 | 0.85 | PTGDR2 (0.67) | PTGDR2PTGIRPTGDR | |
| SCHEMBL8358618 | 0.84 | PTGIR (0.56) | PTGDR2PTGIRALDH1A1 | |
| SCHEMBL8965375 | 0.84 | PTGDR2 (0.63) | PTGDR2PTGIRPTGDR | |
| SCHEMBL8350938 | 0.84 | PTGIR (0.46) | PTGDR2PTGIRKDM4EALDH1A1ALOX15 | |
| SCHEMBL8965035 | 0.81 | PTGDR2 (0.55) | PTGDR2PTGIRPTGDR | |
| SCHEMBL8965748 | 0.81 | PTGIR (0.57) | PTGDR2PTGIRALOX15 | |
| SCHEMBL8965096 | 0.80 | PPARG (0.50) | PTGDR2PTGIRLMNAPTPN7 | |
| SCHEMBL8965101 | 0.80 | PPARG (0.50) | PTGDR2PTGIRLMNAPTPN7 | |
| SCHEMBL8351430 | 0.80 | PTGIR (0.45) | PTGDR2PTGIRLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |