Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965811 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8966128 | 0.90 | GRM4 (0.41) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL9076743 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL9075300 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8965780 | 0.85 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8965791 | 0.85 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8965675 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8965687 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL9143238 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL8965709 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | claimed |