Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966160 | 0.87 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28035425 | 0.86 | TSHR (0.51) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8965784 | 0.84 | TSHR (0.57) | TSHRTHRBALDH1A1 | |
| SCHEMBL17670887 | 0.84 | TSHR (0.35) | TSHRHPGD | |
| SCHEMBL8966166 | 0.83 | TSHR (0.53) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL4464394 | 0.81 | TSHR (0.53) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Methyl Ester SCHEMBL28826459 | 0.81 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL11667567 | 0.81 | TSHR (0.53) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL22554422 | 0.80 | TSHR (0.61) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL700973 | 0.79 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547762-A | THERMOSETTING RESIN LAYER | BRIDGESTONE CORPORATION (JP) | 1996-08-20 | — | — | US | disclosed |