Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1217906 | 0.86 | MEN1 (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL9578924 | 0.84 | TSHR (0.38) | TSHR | |
| SCHEMBL8015188 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL28171004 | 0.80 | TSHR (0.37) | TSHR | |
| SCHEMBL11805769 | 0.80 | TSHR (0.38) | TSHR | |
| SCHEMBL28422225 | 0.78 | TSHR (0.41) | TSHR | |
| SCHEMBL13437510 | 0.77 | ALDH1A1 (0.37) | TSHRMEN1KMT2A | |
| SCHEMBL9187744 | 0.75 | TSHR (0.33) | TSHRMEN1KMT2A | |
| SCHEMBL9657652 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL6986482 | 0.74 | MEN1 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166443-A | PREPARATION OF 2,2-DISUBSTITUTED PENTANE-1,5-DIAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | claimed |
| US-5554787-A | CHEMICAL INTERMEDIATES FOR POLYURETHANES | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| EP-0449110-B1 | 2,2-Dialkylpentane-1,5-diisocyanates, -diurethanes, and -dicarbamic acid chlorides, process for their preparation and their use | BASF AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0452693-B1 | Method of preparing 2,2-disubstituted pentane 1,5-diamines | BASF AG (DE) | 1995-10-04 | — | — | EP | disclosed |
| US-5166443-A | PREPARATION OF 2,2-DISUBSTITUTED PENTANE-1,5-DIAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0452693-A1 | Method of preparing 2,2-disubstituted pentane 1,5-diamines | BASF Aktiengesellschaft (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0449110-A2 | 2,2-Dialkylpentane-1,5-diisocyanates, -diurethanes, and -dicarbamic acid chlorides, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0010179-B1 | PROCESS FOR THE PREPARATION OF 2.2-DIALKYLPENTANE-1.5-DIAMINES, AND THE COMPOUNDS N-(4-CYANO-2.2-DIETHYLBUTYL)-4-CYANO-2.2-DIMETHYL BUTYLIDENE IMINE AND N-(4-CYANO-2-N-BUTYL-2-ETHYLBUTYL)-4-CYANO-2-N-BUTYL-2-ETHYL-BUTYLIDENE IMINE | Ruhrchemie Aktiengesellschaft (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4288350-A | Perfume compositions containing dialkyl delta-lactones | POLAK'S FRUTAL WORKS B.V. (NL) | 1981-09-08 | — | — | US | disclosed |
| EP-0010179-A1 | Process for the preparation of 2.2-dialkylpentane-1.5-diamines, and the compounds N-(4-cyano-2.2-diethylbutyl)-4-cyano-2.2-dimethyl butylidene imine and N-(4-cyano-2-n-butyl-2-ethylbutyl)-4-cyano-2-n-butyl-2-ethyl-butylidene imine | Ruhrchemie Aktiengesellschaft (DE) | 1980-04-30 | — | — | EP | disclosed |
| US-4102913-A | CYANOALKYLATION, ALKALI METAL HYDROXIDE, ACRYLONITRILE | RUHRCHEMIE AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |