SCHEMBL8966027

SCHEMBL8966027

CCOC(=O)C1=C(CC)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
MAPT P10636 3/20 0.52
ALOX15 P16050 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 6/20 0.44
GAA P10253 4/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 3/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 1/20 0.42
MAOA P21397 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 2/20 0.40
MAPK1 P28482 2/20 0.40
FHIT P49789 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6538791 0.88 KDM4E (0.48) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL13469350 0.88 MAPT (0.48) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL5608026 0.86 KDM4E (0.59) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL6902990 0.82 KDM4E (0.32) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL3258907 0.80 SMN1; SMN2 (0.42) KDM4EMAPTALDH1A1GAASMN1; SMN2
SCHEMBL5954131 0.80 KDM4E (0.53) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL1626805 0.80 KDM4E (0.53) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL12555158 0.80 SLC6A2 (0.51) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL433386 0.78 KDM4E (0.52) KDM4EMAPTALOX15MEN1KMT2A
SCHEMBL18092248 0.77 SCD (0.46) KDM4EMAPTALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697028-A1 IMPROVED BONDING RESIN AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-02-21 EP disclosed
WO-1994025527-A2 IMPROVED BONDING RESIN AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-10 WO disclosed