Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17728058 | 0.88 | SCD (0.45) | SCDMAPTLMNAMAPK1DGKA | |
| SCHEMBL10434853 | 0.80 | SCD (0.55) | SCDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9694762 | 0.79 | ALDH1A1 (0.47) | SCDKDM4EMAPTLMNAMAPK1 | |
| SCHEMBL9484047 | 0.78 | SCD (0.52) | SCDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8966027 | 0.77 | KDM4E (0.52) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL5608026 | 0.77 | KDM4E (0.59) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL17728019 | 0.76 | SCD (0.35) | SCDMAPTMEN1KMT2ALMNA | |
| SCHEMBL3678044 | 0.76 | ALDH1A1 (0.51) | KDM4EMAPTLMNAMAPK1ALDH1A1 | |
| SCHEMBL294898 | 0.72 | SCD (0.44) | SCDKDM4EMAPTMEN1ALOX15 | |
| SCHEMBL1626805 | 0.71 | KDM4E (0.53) | KDM4EMAPTMEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3073167-A1 | FLANGE CONNECTION | b.arc GmbH (DE) | 2016-09-28 | — | — | EP | disclosed |