SCHEMBL8966064

SCHEMBL8966064

C=Cc1ccccc1/C=C/CCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.47
CYSLTR1 Q9Y271 2/20 0.47
TSHR P16473 1/20 0.41
SOAT2 O75908 1/20 0.40
SOAT1 P35610 1/20 0.40
FAAH O00519 4/20 0.38
EPHX2 P34913 3/20 0.38
PDE5A O76074 1/20 0.38
CYP2D6 P10635 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38
TRPV1 Q8NER1 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
TNNC1 P63316 1/20 0.37
CHAT P28329 1/20 0.37
PTGS1 P23219 1/20 0.36
PPARG P37231 1/20 0.36
OPRK1 P41145 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489152 1.00 CYSLTR2 (0.47) CYSLTR2CYSLTR1TSHRSOAT2SOAT1
SCHEMBL982344 1.00 CYSLTR2 (0.47) CYSLTR2CYSLTR1TSHRSOAT2SOAT1
SCHEMBL8966073 1.00 CYSLTR2 (0.47) CYSLTR2CYSLTR1TSHRSOAT2SOAT1
SCHEMBL9484250 1.00 CYSLTR2 (0.47) CYSLTR2CYSLTR1TSHRSOAT2SOAT1
SCHEMBL6046925 0.89 CYSLTR2 (0.50) CYSLTR2CYSLTR1SOAT2SOAT1FAAH
SCHEMBL7550543 0.85 TLR8 (0.45) CYSLTR2CYSLTR1TSHRPDE5A
SCHEMBL7550551 0.85 TLR8 (0.45) CYSLTR2CYSLTR1TSHRPDE5A
SCHEMBL29017050 0.85 CYSLTR2 (0.41) CYSLTR2CYSLTR1TSHRSOAT2SOAT1
Hexane SCHEMBL10533800 0.83 ALDH1A1 (0.46) TSHRCNR1CHAT
SCHEMBL21388035 0.83 CYSLTR2 (0.40) CYSLTR2CYSLTR1TSHRSOAT2SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202402-A Catalytic polymerization; cross-linking IDEMITSU KOSAN CO., LTD. (JP) 1993-04-13 US claimed
EP-0311099-B1 STYRENE COPOLYMER AND PROCESS FOR PRODUCING SAID COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-16 EP claimed
EP-0311099-A2 Styrene copolymer and process for producing said copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-04-12 EP claimed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
US-5202402-A Catalytic polymerization; cross-linking IDEMITSU KOSAN CO., LTD. (JP) 1993-04-13 US disclosed
EP-0311099-B1 STYRENE COPOLYMER AND PROCESS FOR PRODUCING SAID COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-16 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
EP-0311099-A2 Styrene copolymer and process for producing said copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-04-12 EP disclosed