Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 13/20 | 1.00 |
| ▸ | CARM1 | Q86X55 | 12/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 2/20 | 0.55 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966097 | 1.00 | PRMT6 (1.00) | PRMT6CARM1BCHEPRMT8TMEM97 | |
| SCHEMBL10145310 | 0.91 | PRMT6 (1.00) | PRMT6CARM1PRMT8TMEM97SIGMAR1 | |
| SCHEMBL13745477 | 0.82 | PRMT6 (0.83) | PRMT6CARM1PRMT8TMEM97SIGMAR1 | |
| SCHEMBL19363866 | 0.81 | KCNH2 (0.74) | PRMT6CARM1TMEM97SIGMAR1CCR3 | |
| Hydrochloric Acid SCHEMBL25367642 | 0.80 | CARM1 (0.67) | PRMT6CARM1BCHEPRMT8SIGMAR1 | |
| SCHEMBL20467905 | 0.80 | PRMT6 (0.79) | PRMT6CARM1PRMT8TMEM97SIGMAR1 | |
| SCHEMBL13554192 | 0.80 | PRMT6 (0.66) | PRMT6CARM1PRMT8SIGMAR1CCR3 | |
| SCHEMBL22844319 | 0.79 | CARM1 (1.00) | PRMT6CARM1PRMT8TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL25366950 | 0.79 | CARM1 (0.65) | PRMT6CARM1PRMT8SIGMAR1CCR3 | |
| SCHEMBL12041389 | 0.78 | KCNH2 (0.84) | PRMT6CARM1TMEM97SIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |