Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107358 | 0.73 | POLB (0.53) | PARP15PARP10TDP1CTSKNPC1 | |
| SCHEMBL4681687 | 0.70 | RECQL (0.59) | SMN1; SMN2 | |
| SCHEMBL4681690 | 0.70 | RECQL (0.59) | SMN1; SMN2 | |
| SCHEMBL289897 | 0.69 | HDAC8 (0.40) | PARP15PARP10TDP1NPC1RAB9A | |
| SCHEMBL2760171 | 0.69 | RAB9A (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4683993 | 0.68 | SMN1; SMN2 (0.53) | TDP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL4683990 | 0.68 | SMN1; SMN2 (0.53) | TDP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL10455929 | 0.67 | GRIN2D (0.59) | LMNA | |
| SCHEMBL8526072 | 0.66 | GRIN2D (0.41) | — | |
| SCHEMBL17536206 | 0.65 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565459-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| EP-0595125-B1 | Substituted aza(cyclo) alkanes and their use as pesticides | BAYER AG (DE) | 1996-05-15 | — | — | EP | disclosed |
| US-5461069-A | Insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-24 | — | — | US | disclosed |
| EP-0595125-A1 | Substituted aza(cyclo) alkanes and their use as pesticides | BAYER AG (DE) | 1994-05-04 | — | — | EP | disclosed |