Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966515 | 1.00 | RAB9A (0.75) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| Hydrochloric Acid SCHEMBL8613532 | 0.98 | RAB9A (0.73) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| Hydrochloric Acid SCHEMBL8613530 | 0.98 | RAB9A (0.73) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL17461333 | 0.86 | RAB9A (1.00) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL372256 | 0.86 | RAB9A (1.00) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL372255 | 0.86 | RAB9A (1.00) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL6421753 | 0.84 | RAB9A (0.75) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL4936531 | 0.84 | RAB9A (0.75) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL5717723 | 0.84 | RAB9A (0.75) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB | |
| SCHEMBL6421749 | 0.84 | RAB9A (0.75) | RAB9AKMT2ASMN1; SMN2KDM4EPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561147-A | ANTIINFLAMMATORY AGENT, ANTIPYRETIC, ANALGESICS, ANTIALLERGENS, IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| EP-0522606-B1 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0612729-A2 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5246948-A | Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0522606-A2 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |