Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.63 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8613533 | 0.98 | MGAM (0.61) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL11419833 | 0.85 | MGAM (0.70) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL30475741 | 0.84 | MGAM (0.63) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL4936523 | 0.84 | MGAM (0.63) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL336044 | 0.83 | MGAM (0.71) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| Hydrochloric Acid SCHEMBL7902952 | 0.81 | MGAM (0.69) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL28818314 | 0.80 | MGAM (0.90) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL4815422 | 0.80 | MGAM (0.71) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| SCHEMBL7371232 | 0.79 | MGAM (0.76) | MGAMCFTRTOP2ATOP2BBCAT1 | |
| Formaldehyde SCHEMBL28117649 | 0.78 | MGAM (0.93) | MGAMCFTRTOP2ATOP2BBCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561147-A | ANTIINFLAMMATORY AGENT, ANTIPYRETIC, ANALGESICS, ANTIALLERGENS, IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| EP-0522606-B1 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0612729-A2 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5246948-A | Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0522606-A2 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |