Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.71 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7902952 | 0.98 | MGAM (0.69) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL28818314 | 0.86 | MGAM (0.90) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL7371232 | 0.85 | MGAM (0.76) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL28048 | 0.83 | MGAM (1.00) | MGAMCFTRKDRTOP2ATOP2B | |
| Bromide SCHEMBL7374451 | 0.83 | MGAM (0.73) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL4816887 | 0.83 | MGAM (0.73) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL29362407 | 0.83 | MGAM (1.00) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL8966520 | 0.83 | MGAM (0.63) | MGAMCFTRKDRTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL8613533 | 0.82 | MGAM (0.61) | MGAMCFTRKDRTOP2ATOP2B | |
| SCHEMBL4815422 | 0.81 | MGAM (0.71) | MGAMCFTRKDRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831566-B | A kind of preparation method of the chloro- 3- formyl quinoline analog derivative of 2- | 三峡大学 | 2019-11-08 | — | — | CN | claimed |
| CN-106831566-A | A kind of preparation method of the formyl quinoline analog derivative of 2 chlorine 3 | 三峡大学 | 2017-06-13 | — | — | CN | claimed |
| US-12486234-B2 | PAPD5 inhibitors and methods of use thereof | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-12-02 | — | — | US | disclosed |
| WO-2025079680-A1 | NEUROPROTECTIVE AGENT | 国立研究開発法人国立精神・神経医療研究センター | 2025-04-17 | — | — | WO | disclosed |
| CN-118221579-A | PRMT5 inhibitors | 北京望实智慧科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118201920-A | PAPD5 inhibitors and methods of use thereof | 儿童医疗中心公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116478129-A | Quinoline compound and use thereof | 深圳默元生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20220274928-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION | 2022-09-01 | — | — | US | disclosed |
| CN-105884685-B | Monomer, organic layer composition, organic layer, and method of forming pattern | 三星SDI株式会社 | 2020-03-31 | — | — | CN | disclosed |
| US-10561748-B2 | Anthranilic acid derivatives | MAHESHWARI DIVYA (IN) | 2020-02-18 | — | — | US | disclosed |
| US-20190343827-A1 | DEUTERATED ANALOGS OF TARIQUIDAR | IZUMI TECHNOLOGY, LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-4885295-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | STERLING DRUG INC. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0292990-A1 | 4-Halopyridine-3-carboxamide compounds and herbicidal composition thereof | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| US-RE32761-E | ANALGESICS, ANTIRHEUMATIC AND ANTIINFLAMMATORY AGENT | STERLING DRUG INC. (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0085392-B1 | SUNLIGHT-ENERGY-STORING SUBSTANCES AND SUNLIGHT-ENERGY-STORING METHOD USING THE SAME | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1987-01-21 | — | — | EP | disclosed |
| US-4634776-A | ANALGESIC, ANTIRHEUMATIC, ANTIINFLAMMATORY | STERLING DRUG, INC. (US) | 1987-01-06 | — | — | US | disclosed |
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0171037-A2 | 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof | STERLING WINTHROP INC. (US) | 1986-02-12 | — | — | EP | disclosed |
| US-4449516-A | Sunlight-energy-storing method | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| EP-0085392-A2 | Sunlight-energy-storing substances and sunlight-energy-storing method using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1983-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190343827-A1 | DEUTERATED ANALOGS OF TARIQUIDAR | ABCG2, ABCB11, ALPP | MGAM 4532/4885CFTR 363/4885KDR 2320/4885 |
| US-20220274928-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | POT1, PARP15, TERT | MGAM 2407/4885CFTR 3846/4885KDR 4723/4885 |
| US-12486234-B2 | PAPD5 inhibitors and methods of use thereof | POT1, PARP15, TERT | MGAM 2407/4885CFTR 3846/4885KDR 4723/4885 |
| US-10561748-B2 | Anthranilic acid derivatives | SLC47A1, ABCC1, ABCB1 | MGAM 4005/4885CFTR 953/4885KDR 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.