Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967182 | 1.00 | SPHK1 (0.57) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| SCHEMBL8501701 | 0.89 | SPHK1 (0.54) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| Hydrochloric Acid SCHEMBL8501504 | 0.87 | SPHK1 (0.52) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| SCHEMBL11664454 | 0.84 | HTR2A (0.66) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| SCHEMBL12502918 | 0.84 | HTR2A (0.66) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| Hydrochloric Acid SCHEMBL27921087 | 0.83 | HTR2A (0.64) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| SCHEMBL8501713 | 0.82 | SPHK1 (0.50) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| SCHEMBL8501636 | 0.82 | SPHK1 (0.50) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| Hydrochloric Acid SCHEMBL8503317 | 0.82 | SPHK1 (0.48) | SPHK1HTR2AESR1ADRA2AADORA3 | |
| SCHEMBL8503490 | 0.82 | SPHK1 (0.50) | SPHK1HTR2AESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432661-B1 | 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same | YASHIMA KAGAKU KOGYO KK (JP) | 1996-03-06 | — | — | EP | disclosed |
| US-5141948-A | 2-SUBSTITUTED PHENYL-2-OXAZOLINE OR THIAZOLINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND INSECTICIDES AND ACARICIDES CONTAINING THE SAME | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0432661-A2 | 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |