SCHEMBL8966980

SCHEMBL8966980

O=CC1CC1c1ccc(Cl)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 13/20 0.47
SLC6A2 P23975 9/20 0.47
SLC6A4 P31645 8/20 0.44
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9519029 1.00 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4ALDH1A1
SCHEMBL2320349 0.84 SLC6A2 (0.41) SLC6A3SLC6A2SLC6A4ALDH1A1
SCHEMBL9515307 0.82 SLC6A3 (0.43) SLC6A3SLC6A2SLC6A4ALDH1A1
SCHEMBL9515301 0.82 SLC6A3 (0.43) SLC6A3SLC6A2SLC6A4ALDH1A1
SCHEMBL9515312 0.82 SLC6A3 (0.43) SLC6A3SLC6A2SLC6A4ALDH1A1
SCHEMBL3647911 0.81 SLC6A2 (0.49) SLC6A3SLC6A2SLC6A4
SCHEMBL9515685 0.79 SLC6A3 (0.40) SLC6A3SLC6A2SLC6A4
SCHEMBL9515691 0.79 SLC6A3 (0.40) SLC6A3SLC6A2SLC6A4
SCHEMBL9515670 0.79 SLC6A3 (0.40) SLC6A3SLC6A2SLC6A4
SCHEMBL9515677 0.79 SLC6A3 (0.40) SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553081-B1 PESTICIDES ROUSSEL UCLAF (FR) 1996-02-28 EP disclosed
US-5326755-A Contain cyclopropane ring ROUSSEL UCLAF 1994-07-05 US disclosed
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
EP-0553081-A1 PESTICIDES. ROUSSEL UCLAF (FR) 1993-08-04 EP disclosed
WO-1991016301-A1 PESTICIDES THE WELLCOME FOUNDATION LIMITED (GB) 1991-10-31 WO disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed