Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967592 | 0.90 | TP53 (0.37) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL8850030 | 0.88 | TSHR (0.56) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL8967689 | 0.87 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL8967703 | 0.87 | GBA1 (0.39) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL8966995 | 0.86 | TP53 (0.40) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL8967417 | 0.81 | TSHR (0.40) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL9479114 | 0.77 | TSHR (0.46) | ALDH1A1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL8967693 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL8967775 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL6858467 | 0.72 | TSHR (0.62) | ALDH1A1TP53TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458296-B1 | Modified epoxy resins having acetylenically unsaturated functions | NIPPON PAINT CO LTD (JP) | 1996-03-06 | — | — | EP | disclosed |
| US-5242996-A | MODIFIED EPOXY RESINS HAVING ACETYLENICALLY UNSATURATED FUNCTIONS | NIPPON PAINT CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0458296-A2 | Modified epoxy resins having acetylenically unsaturated functions | NIPPON PAINT CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |