SCHEMBL8967103

SCHEMBL8967103

CCCCCCCCCCCCOC(=O)NC(=S)OCC(C)C

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.51
ACHE P22303 12/20 0.46
NAAA Q02083 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5161708 0.94 EPHX1 (0.47) EPHX1ACHENAAACA12CA1
SCHEMBL5162972 0.94 NPC1 (0.42) EPHX1ACHE
SCHEMBL4882104 0.87 EPHX1 (0.61) EPHX1ACHENAAACA12CA1
SCHEMBL2942928 0.87 EPHX1 (0.61) EPHX1ACHENAAACA12CA1
SCHEMBL5162543 0.85 EPHX1 (0.59) EPHX1ACHENAAACA12CA1
SCHEMBL5164102 0.84 EPHX1 (0.56) EPHX1ACHENAAACA12CA1
SCHEMBL5161738 0.82 ALDH1A1 (0.44)
SCHEMBL4874522 0.81 EPHX1 (0.53) EPHX1ACHENAAACA12CA1
SCHEMBL5161710 0.80 ALDH1A1 (0.41)
SCHEMBL4430601 0.80 EPHX1 (0.50) EPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0550182-B1 Lubricating oil containing antiwear/antioxidant additive EXXON RESEARCH ENGINEERING CO (US) 1996-07-03 EP disclosed
EP-0546829-B1 Lubricating oil containing antiwear/antioxidant additive EXXON RESEARCH ENGINEERING CO (US) 1996-02-28 EP disclosed
EP-0550182-A1 Lubricating oil containing antiwear/antioxidant additive EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-07-07 EP disclosed
EP-0546829-A1 Lubricating oil containing antiwear/antioxidant additive EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-06-16 EP disclosed
US-5219478-A Oil additives imparting wear and oxidation resistance; internal combustion engines EXXON RESEARCH AND ENGINEERING CO. (US) 1993-06-15 US disclosed
US-5160644-A Wear and oxidation resistance EXXON RESEARCH AND ENGINEERING CO. (US) 1992-11-03 US disclosed