SCHEMBL8967131

SCHEMBL8967131

CC(/C=C/[C@]1(F)CC1c1ccc(Cl)c(Cl)c1)=C\C(=O)N(CC(C)C)Sc1ccc(C(C)(C)C)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8967137 0.92 SLC6A2 (0.30) SLC6A2SLC6A4
SCHEMBL9400367 0.90 SLC6A4 (0.33) SLC6A2SLC6A4
SCHEMBL8967117 0.90 SLC6A4 (0.33) SLC6A2SLC6A4
SCHEMBL8967676 0.83
SCHEMBL8967135 0.81
SCHEMBL8967153 0.80 SLC6A4 (0.33) SLC6A2SLC6A4
SCHEMBL9515299 0.73 HPGD (0.40) SLC6A2SLC6A4
SCHEMBL8967163 0.73 SLC6A3 (0.36) SLC6A2SLC6A4
SCHEMBL8967154 0.73 SLC6A3 (0.36) SLC6A2SLC6A4
SCHEMBL8967152 0.73 SLC6A3 (0.36) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553081-B1 PESTICIDES ROUSSEL UCLAF (FR) 1996-02-28 EP claimed
EP-0553081-B1 PESTICIDES ROUSSEL UCLAF (FR) 1996-02-28 EP disclosed
US-5326755-A Contain cyclopropane ring ROUSSEL UCLAF 1994-07-05 US disclosed