Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967569 | 0.98 | HRH3 (0.54) | HRH3MEN1KMT2AATML3MBTL1 | |
| SCHEMBL10100371 | 0.96 | HRH3 (0.50) | HRH3MEN1KMT2AATML3MBTL1 | |
| SCHEMBL8967124 | 0.92 | HRH3 (0.50) | HRH3MEN1KMT2AKCNH2L3MBTL1 | |
| SCHEMBL9917380 | 0.92 | HRH3 (0.50) | HRH3MEN1KMT2AKCNH2L3MBTL1 | |
| SCHEMBL9917280 | 0.90 | MEN1 (0.50) | HRH3MEN1KMT2AL3MBTL1 | |
| SCHEMBL22509507 | 0.86 | MEN1 (0.46) | HRH3MEN1KMT2AL3MBTL1 | |
| SCHEMBL20328700 | 0.85 | HRH3 (0.44) | HRH3MEN1KMT2AKCNH2 | |
| SCHEMBL20328709 | 0.85 | HRH3 (0.47) | HRH3MEN1KMT2AKCNH2 | |
| SCHEMBL29325698 | 0.85 | ALDH1A1 (0.46) | HRH3MEN1KMT2A | |
| SCHEMBL22520687 | 0.85 | ALDH1A1 (0.46) | HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348964-A | Anticholesterol agents or fungicides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-20 | — | — | US | claimed |
| EP-0468434-B1 | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis | MERRELL DOW PHARMA (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5348964-A | Anticholesterol agents or fungicides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-20 | — | — | US | disclosed |
| CN-1058399-A | New piperidine ether and thioether as cholesteral biosynthesis inhibitor | MERRELL DOW PHARMA (US) | 1992-02-05 | — | — | CN | disclosed |
| EP-0468434-A1 | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |