Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9090924 | 0.88 | CHRNA7 (0.44) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL8967765 | 0.81 | CHRNA7 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL8967406 | 0.79 | CHRNA7 (0.42) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL8541939 | 0.79 | CHRNA7 (0.42) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL8900770 | 0.79 | MEN1 (0.44) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL8541943 | 0.79 | CHRNA7 (0.42) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL8546489 | 0.79 | CHRNA7 (0.42) | SLC6A2SLC6A4SLC6A3CHRNA7KDM1A | |
| SCHEMBL16944115 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20629955 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6927678 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508424-A | REDUCED SIDE EFFECTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |