Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323180 | 1.00 | TSHR (0.55) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL444104 | 1.00 | TSHR (0.55) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL6989159 | 0.91 | TP53 (0.50) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL17706564 | 0.86 | TP53 (0.46) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL11459690 | 0.83 | ADORA3 (0.52) | TSHRTP53EBPSIGMAR1ACACB | |
| SCHEMBL10454154 | 0.82 | TP53 (0.38) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL6381994 | 0.82 | TSHR (0.52) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL29160521 | 0.81 | TP53 (0.68) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL6044363 | 0.81 | TP53 (0.51) | TSHRTP53EBPSIGMAR1RECQL | |
| SCHEMBL6044360 | 0.81 | TP53 (0.51) | TSHRTP53EBPSIGMAR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304388-A | Asymmetric synthesis method of (R)- or (S)-Lily aldehyde | FOURTH MILITARY MEDICAL UNIV | 2013-09-18 | — | — | CN | claimed |
| CN-103304388-A | Asymmetric synthesis method of (R)- or (S)-Lily aldehyde | FOURTH MILITARY MEDICAL UNIV | 2013-09-18 | — | — | CN | disclosed |
| EP-0530336-B1 | CHIRAL PHOSPHINES | HOFFMANN LA ROCHE (CH) | 1996-03-06 | — | — | EP | disclosed |
| US-5274125-A | Chirale phosphines | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0530336-A1 | CHIRAL PHOSPHINES. | HOFFMANN LA ROCHE (CH) | 1993-03-10 | — | — | EP | disclosed |
| WO-1992016536-A1 | CHIRAL PHOSPHINES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-01 | — | — | WO | disclosed |