SCHEMBL8967453

SCHEMBL8967453

O=C1NC(=O)c2c(CCCCCO)cccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CCNE2 O96020 2/20 0.39
CDK4 P11802 2/20 0.39
CCND1 P24385 2/20 0.39
CCNE1 P24864 2/20 0.39
CDK2 P24941 2/20 0.39
GSK3B P49841 2/20 0.38
WEE1 P30291 2/20 0.37
PARP1 P09874 1/20 0.37
GSK3A P49840 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
CASP3 P42574 6/20 0.36
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17633986 1.00 KDM4E (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL28249127 1.00 KDM4E (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL31035989 1.00 KDM4E (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL7403092 0.98 KDM4E (0.42) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL6598413 0.94 KDM4E (0.43) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL11015946 0.92 GSK3B (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL10914947 0.92 GSK3B (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL10712855 0.92 GSK3B (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL11206986 0.92 GSK3B (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL1424202 0.87 KDM4E (0.45) KDM4EALDH1A1GAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119053604-A Heterocyclic compounds for the treatment of ERK5 mediated diseases 癌症研究技术有限公司 2024-11-29 CN disclosed
CN-103497337-A Preparation method of polythioetherimide NINGBO INST MATERIALS TECHNOLOGY & ENG CAS 2014-01-08 CN disclosed
US-5530089-A Polysulfoneimides THE BOEING COMPANY (US) 1996-06-25 US disclosed
US-5268519-A Lightly crosslinked etherimide oligomers THE BOEING COMPANY (US) 1993-12-07 US disclosed
US-5175304-A Solvent resistant cured composite THE BOEING COMPANY (US) 1992-12-29 US disclosed
US-5144000-A Method for forming crosslinking polyetherimide oligomers THE BOEING COMPANY (US) 1992-09-01 US disclosed
US-4990624-A Intermediates anhydrides useful for synthesizing etherimides THE BOEING COMPANY (US) 1991-02-05 US disclosed
US-4981922-A Blended etherimide oligomers THE BOEING COMPANY (US) 1991-01-01 US disclosed
US-4958031-A ENDCAPPING POLYETHERIMIDE COPOLYMERS THE BOEING COMPANY (US) 1990-09-18 US disclosed
US-4851495-A Polyetherimide oligomer THE BOEING COMPANY (US) 1989-07-25 US disclosed
EP-0283636-A2 Polyetherimide oligomers and blends THE BOEING COMPANY (US) 1988-09-28 EP disclosed
US-4705892-A Process for preparing alpha,omega-diamino acids MERCK & CO., INC. (US) 1987-11-10 US disclosed
US-4297474-A MOLDING MATERIALS; COATINGS; FILMS GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed
US-4297474-A MOLDING MATERIALS; COATINGS; FILMS GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed
US-4297474-A MOLDING MATERIALS; COATINGS; FILMS GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed