SCHEMBL8967485

SCHEMBL8967485

CC(C)=CCC/C(C)=C/CC/C(C)=C/CONC(=O)C(CP(=O)(O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 17/20 0.72
PGGT1B P53609 5/20 0.72
FNTB P49356 14/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550276 1.00 FNTA (0.72) FNTAPGGT1BFNTB
SCHEMBL8967490 1.00 FNTA (0.72) FNTAPGGT1BFNTB
SCHEMBL6550284 1.00 FNTA (0.72) FNTAPGGT1BFNTB
SCHEMBL6549891 0.86 FNTA (0.60) FNTAPGGT1BFNTB
SCHEMBL6550427 0.84 FNTA (1.00) FNTAPGGT1BFNTB
SCHEMBL6550440 0.84 FNTA (1.00) FNTAPGGT1BFNTB
SCHEMBL6550448 0.81 FNTA (1.00) FNTAPGGT1BFNTB
SCHEMBL6550444 0.81 FNTA (1.00) FNTAPGGT1BFNTB
SCHEMBL8967585 0.81 FNTA (1.00) FNTAPGGT1BFNTB
SCHEMBL6551251 0.81 FNTA (1.00) FNTAPGGT1BFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523430-A Protein farnesyl transferase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1996-06-04 US disclosed