SCHEMBL8967699

SCHEMBL8967699

O=C(O)CN(CP(=O)(O)O)C(=O)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MVD P53602 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11215879 0.98 MEN1 (0.32) MEN1LMNAHPGDTSHRBLM
SCHEMBL9627216 0.83
SCHEMBL11344184 0.83
SCHEMBL10930043 0.80 MVD (0.31) MVD
SCHEMBL10810925 0.79
SCHEMBL7876936 0.77 TDP1 (0.46) MEN1LMNAHPGDTSHRBLM
SCHEMBL6794530 0.77 TDP1 (0.40) MEN1LMNAHPGDTSHRBLM
SCHEMBL11061603 0.76
SCHEMBL10809670 0.75
SCHEMBL10929971 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523430-A Protein farnesyl transferase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1996-06-04 US disclosed
US-4652297-A HERBICIDES MONSANTO COMPANY (US) 1987-03-24 US disclosed
EP-0060132-B1 N-FORMYL-N-PHOSPHONOMETHYLGLYCINE AND ESTERS THEREOF AS HERBICIDES MONSANTO COMPANY (US) 1985-07-17 EP disclosed
US-4496389-A PREEMERGENCE, POSTEMERGENCE HERBICIDES MONSANTO COMPANY (US) 1985-01-29 US disclosed
US-4496389-A PREEMERGENCE, POSTEMERGENCE HERBICIDES MONSANTO COMPANY (US) 1985-01-29 US disclosed
US-4421549-A HERBICIDES MONSANTO COMPANY (US) 1983-12-20 US disclosed
EP-0007211-B1 DERIVATIVES OF N-TRIFLUOROACETYL-N-PHOSPHONOMETHYLGLYCINATES AND THE HERBICIDAL USE THEREOF MONSANTO COMPANY (US) 1983-09-21 EP disclosed
EP-0007211-B1 DERIVATIVES OF N-TRIFLUOROACETYL-N-PHOSPHONOMETHYLGLYCINATES AND THE HERBICIDAL USE THEREOF MONSANTO COMPANY (US) 1983-09-21 EP disclosed
EP-0031714-B1 AMIDO AND HYDRAZIDO DERIVATIVES OF N-PHOSPHINOTHIOYLMETHYLGLYCINE ESTERS AND HERBICIDAL COMPOSITIONS CONTAINING THEM MONSANTO COMPANY (US) 1983-07-27 EP disclosed
US-4359332-A Amide and hydrazide derivatives of N-trifluoroacetyl-N-phosphonomethylglycine as herbicides MONSANTO COMPANY (US) 1982-11-16 US disclosed
EP-0007210-A2 Ester derivatives of N-trifluoro-acetyl-N-phosphonomethylglycine and the herbicidal use thereof MONSANTO COMPANY (US) 1980-01-23 EP disclosed
EP-0007210-A2 Ester derivatives of N-trifluoro-acetyl-N-phosphonomethylglycine and the herbicidal use thereof MONSANTO COMPANY (US) 1980-01-23 EP disclosed
US-4180394-A Derivatives of N-trifluoroacetyl-N-phosphonomethylglycinates and the herbicidal use thereof MONSANTO COMPANY (US) 1979-12-25 US disclosed
US-4180394-A Derivatives of N-trifluoroacetyl-N-phosphonomethylglycinates and the herbicidal use thereof MONSANTO COMPANY (US) 1979-12-25 US disclosed
US-4180394-A Derivatives of N-trifluoroacetyl-N-phosphonomethylglycinates and the herbicidal use thereof MONSANTO COMPANY (US) 1979-12-25 US disclosed
US-4175946-A HERBICIDES MONSANTO COMPANY (US) 1979-11-27 US disclosed
US-4175946-A HERBICIDES MONSANTO COMPANY (US) 1979-11-27 US disclosed
EP-0005321-A1 Derivatives of N-trifluoroacetyl N-phosphonomethylglycine dichloride, their preparation and their use as herbicides MONSANTO COMPANY (US) 1979-11-14 EP disclosed
EP-0005321-A1 Derivatives of N-trifluoroacetyl N-phosphonomethylglycine dichloride, their preparation and their use as herbicides MONSANTO COMPANY (US) 1979-11-14 EP disclosed
EP-0005321-A1 Derivatives of N-trifluoroacetyl N-phosphonomethylglycine dichloride, their preparation and their use as herbicides MONSANTO COMPANY (US) 1979-11-14 EP disclosed