Sugi Predict

Sugi Predict / Compounds / SCHEMBL6794530

SCHEMBL6794530

SCHEMBL6794530

O=C(O)CN(CP(=O)(O)O)C(=O)N(CC(=O)O)CP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.40
▸ LMNA P02545 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ BLM P54132 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ EYA2 O00167 1/20 0.35
▸ APP P05067 1/20 0.35
▸ ACE P12821 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.33
▸ CHRM2 P08172 1/20 0.33
▸ ADRA2A P08913 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ DRD1 P21728 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ ADRA1A P35348 1/20 0.33
▸ DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7876936 0.86 TDP1 (0.46) TDP1LMNATSHRBLMMEN1
SCHEMBL249304 0.82 TDP1 (0.37) TDP1LMNATSHRBLMMEN1
SCHEMBL11324627 0.80 PHF8 (0.39) TDP1LMNATSHRBLMMEN1
SCHEMBL7763569 0.79 ENO1 (0.35) TDP1LMNATSHRBLMMEN1
SCHEMBL2988195 0.79 TDP1 (0.34) TDP1LMNATSHRBLMMEN1
SCHEMBL4750608 0.77 MEN1 (0.33) TDP1LMNATSHRBLMMEN1
SCHEMBL8967699 0.77 MEN1 (0.33) TDP1LMNATSHRBLMMEN1
SCHEMBL7875291 0.77 MVD (0.33) TDP1LMNATSHRBLMMEN1
SCHEMBL6792984 0.76 TDP1 (0.47) TDP1LMNATSHRBLMEYA2
SCHEMBL11314817 0.76 TSHR (0.33) TDP1LMNATSHRBLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6759549-B2 PREPARATION OF N-(PHOSPHONOMETHYL)GLYCINE, ITS SALTS, AND ITS ESTERS, WHEREIN THE METHOD OF PREPARATION COMPRISES A CARBOXYMETHYLATION STEP MONSANTO TECHNOLOGY LLC 2004-07-06 — — US disclosed
US-20030225298-A1 Method of preparing amino carboxylic acids MONSANTO TECHNOLOGY LLC 2003-12-04 — — US disclosed
US-20030088122-A1 Method of preparing amino carboxylic acids JOHNSON TODD J (US) 2003-05-08 — — US disclosed
US-20020002281-A1 Method of preparing amino carboxylic acids JOHNSON TODD J (US) 2002-01-03 — — US disclosed
US-6265605-B1 ADDITIVE IN PROCESSED MEAT, BEVERAGES, AND IN OTHER PROCESSED FOOD STUFFS; AS INTERMEDIATES IN DRUGS, AGRICULTURAL CHEMICALS AND PESTICIDES, HERBICIDES MONSANTO COMPANY 2001-07-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020002281-A1 Method of preparing amino carboxylic acids CPS1, GNMT, HNMT TDP1 3962/4885LMNA 622/4885TSHR 4563/4885
US-20030088122-A1 Method of preparing amino carboxylic acids CPS1, GNMT, HNMT TDP1 3962/4885LMNA 622/4885TSHR 4563/4885
US-20030225298-A1 Method of preparing amino carboxylic acids CPS1, GNMT, HNMT TDP1 3962/4885LMNA 622/4885TSHR 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.