Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538702 | 0.81 | ACHE (0.50) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL1538792 | 0.81 | ACHE (0.50) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL3157907 | 0.79 | ACHE (0.47) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL987122 | 0.78 | ACHE (0.53) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL24624112 | 0.77 | ACHE (0.44) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL1538778 | 0.77 | ACHE (0.44) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL1538886 | 0.77 | ACHE (0.44) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL24624089 | 0.75 | ACHE (0.42) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL13231686 | 0.73 | ACHE (0.57) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL4073452 | 0.73 | ACHE (0.57) | ACHETDP1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514034-B1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0514034-A1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5120520-A | In presence of metal or metal-contianing catalyst | DOW CORNING CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |