Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983713 | 0.87 | LMNA (0.31) | LMNAHSD17B10 | |
| SCHEMBL12345343 | 0.82 | — | — | |
| SCHEMBL1277109 | 0.80 | TSHR (0.46) | TSHRALDH1A1 | |
| SCHEMBL8690770 | 0.78 | MAPT (0.32) | TSHR | |
| SCHEMBL23132548 | 0.78 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL3292585 | 0.78 | — | — | |
| SCHEMBL999119 | 0.77 | — | — | |
| SCHEMBL29018424 | 0.76 | — | — | |
| SCHEMBL12469806 | 0.76 | TSHR (0.48) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL9451200 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038249-C | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM & HAAS (US) | 1998-05-06 | — | — | CN | disclosed |
| US-5554787-A | CHEMICAL INTERMEDIATES FOR POLYURETHANES | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| CN-1069729-A | Dihydropyridazinone, pyridazinone and related compound thereof as sterilant | ROHM & HAAS (US) | 1993-03-10 | — | — | CN | disclosed |