Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.50 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | PDXK | O00764 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005970 | 0.94 | HPGD (0.58) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL140749 | 0.91 | HPGD (0.61) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL29040292 | 0.90 | HPGD (0.59) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL31536462 | 0.86 | HPGD (0.55) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL4612067 | 0.86 | HPGD (0.58) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL2133601 | 0.83 | HPGD (0.55) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL43879 | 0.83 | KDM4E (0.83) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL29004449 | 0.83 | KDM4E (0.83) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL22857703 | 0.82 | HPGD (0.56) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| Pyridoxine SCHEMBL31241297 | 0.81 | KDM4E (0.80) | HPGDKDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863716-A | PARAMAGNETIC MATERIAL FOR INJECTION | SALUTAR, INC. (US) | 1989-09-05 | — | — | US | claimed |
| EP-0515638-B1 | NOVEL PREORGANIZED HEXADENTATE LIGANDS USEFUL IN RADIOGRAPHIC IMAGING AGENTS | MALLINCKRODT MEDICAL INC (US) | 1996-03-06 | — | — | EP | disclosed |
| EP-0290047-B1 | Dipyridoxyl phosphate nuclear magnetic resonance imagery contrast agents | NYCOMED SALUTAR INC (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0290041-B1 | Radioactive metal chelates of dipyridoxyl phosphate | NYCOMED SALUTAR INC (US) | 1993-12-08 | — | — | EP | disclosed |
| US-5223243-A | Dipyridoxyl phosphate chelating compound intermediates useful as NMRI contrast agents | SALUTAR, INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0543872-A1 | NEW USE OF COMPLEX SALTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003168-A1 | NEW USE OF COMPLEX SALTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-03-05 | — | — | WO | disclosed |
| US-5091169-A | Water soluble, stable chelates with paramagnetic metal ions | SALUTAR, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-4992554-A | Used as contrast agent in nuclear magnetic resonance imagery | SALUTAR, INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4933456-A | STABLE, SOLUBLE | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4933456-A | STABLE, SOLUBLE | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4863716-A | PARAMAGNETIC MATERIAL FOR INJECTION | SALUTAR, INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4842845-A | Radioactive metal chelates for dipyridoxyl phosphate | SALUTAR, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0290041-A2 | Radioactive metal chelates of dipyridoxyl phosphate | NYCOMED SALUTAR, INC. (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0290047-A2 | Dipyridoxyl phosphate nuclear magnetic resonance imagery contrast agents | NYCOMED SALUTAR, INC. (US) | 1988-11-09 | — | — | EP | disclosed |