Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8542852 | 1.00 | SLC9A1 (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| Oxalic Acid SCHEMBL8967918 | 1.00 | SLC9A1 (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| Oxalic Acid SCHEMBL8542854 | 1.00 | SLC9A1 (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| Oxalic Acid SCHEMBL8542524 | 0.81 | HTR2C (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| Oxalic Acid SCHEMBL8542517 | 0.81 | HTR2C (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| Oxalic Acid SCHEMBL8967339 | 0.81 | HTR2C (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| Oxalic Acid SCHEMBL8967344 | 0.81 | HTR2C (0.44) | SLC9A1ALDH1A1HTR2CFFAR1HTR2A | |
| SCHEMBL9392921 | 0.72 | HTR2C (0.50) | SLC9A1HTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL9392916 | 0.72 | HTR2C (0.50) | SLC9A1HTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL11548317 | 0.71 | DDB1 (0.47) | SLC9A1HTR2CHTR2AHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508424-A | REDUCED SIDE EFFECTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |