⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336874 | 0.68 | NPC1 (0.34) | — | |
| SCHEMBL2009985 | 0.65 | — | — | |
| SCHEMBL208590 | 0.64 | — | — | |
| SCHEMBL28894062 | 0.64 | APOBEC3A (0.39) | — | |
| Hydrochloric Acid SCHEMBL27997285 | 0.64 | DRD2 (0.30) | — | |
| SCHEMBL208652 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL27993924 | 0.63 | — | — | |
| SCHEMBL20892468 | 0.60 | — | — | |
| SCHEMBL30565541 | 0.59 | — | — | |
| SCHEMBL10175407 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217974-A1 | ISOQUINOLONE COMPOUND AND USE THEREOF | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| EP-3650449-B1 | FXR RECEPTOR AGONIST | XUANZHU BIOPHARMACEUTICAL CO LTD (CN) | 2023-08-23 | — | — | EP | disclosed |
| EP-2264043-B1 | Heterobifunctional pan-selectin inhibitors | GLYCOMIMETICS INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20170158680-A1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-08 | — | — | US | disclosed |
| US-20170158680-A1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-08 | — | — | US | disclosed |
| EP-3115361-A1 | HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD AND USE THEREOF | Shanghai Institute Of Materia Medica Chinese Academy of Sciences (CN) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015131856-A1 | HETEROCYCLIC COMPOUNDS, AND PREPARATION METHOD AND USE THEREOF | 中国科学院上海药物研究所 | 2015-09-11 | — | — | WO | disclosed |
| US-20130005710-A1 | AMINOPYRIDINE DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-01-03 | — | — | US | disclosed |
| EP-2502909-A1 | AMINOPYRIDINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-09-26 | — | — | EP | disclosed |
| EP-2478981-A1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | Sumitomo Chemical Co., Ltd (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-0584816-B1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (IV) | EASTMAN KODAK CO (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0584815-B1 | High tabularity high chloride emulsions of exceptional stability | EASTMAN KODAK CO (US) | 1996-03-06 | — | — | EP | disclosed |
| EP-0551866-B1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion | EASTMAN KODAK CO (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0584816-A1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (IV) | EASTMAN KODAK COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584815-A1 | High tabularity high chloride emulsions of exceptional stability | EASTMAN KODAK COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0551866-A1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion | EASTMAN KODAK COMPANY (US) | 1993-07-21 | — | — | EP | disclosed |
| EP-0533189-A1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (I) | EASTMAN KODAK COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |