Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.71 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 7/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297061 | 0.93 | CYP4F2 (0.65) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL20613520 | 0.88 | CYP4F2 (0.73) | CYP4F2CYP4A11ALDH1A1LMNAKMT2A | |
| SCHEMBL22098378 | 0.83 | CYP4F2 (1.00) | CYP4F2CYP4A11TDP1MEN1KMT2A | |
| SCHEMBL22098215 | 0.83 | CYP4F2 (1.00) | CYP4F2CYP4A11TDP1MEN1KMT2A | |
| SCHEMBL20730090 | 0.81 | CYP4F2 (0.97) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A | |
| SCHEMBL20597647 | 0.81 | CYP4F2 (0.73) | CYP4F2CYP4A11 | |
| SCHEMBL22070954 | 0.81 | CYP4F2 (0.96) | CYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL3150942 | 0.81 | CYP4F2 (0.72) | CYP4F2CYP4A11MEN1KMT2A | |
| Adipic Acid SCHEMBL4555700 | 0.80 | CYP2C19 (0.50) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL9437316 | 0.80 | CYP2C19 (0.50) | CYP4F2CYP4A11ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550262-A | TREATMENT OF MUSCLES WASTING DISEASES | CEPHALON, INC. (US) | 1996-08-27 | — | — | US | disclosed |