Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924907 | 0.80 | KCNH2 (0.33) | CHRNA7KCNH2 | |
| SCHEMBL8556163 | 0.79 | CHRNA7 (0.36) | CHRNA7KCNH2 | |
| SCHEMBL9561693 | 0.75 | CHRNA7 (0.34) | CHRNA7KCNH2 | |
| SCHEMBL23951881 | 0.71 | MEN1 (0.37) | SIGMAR1 | |
| SCHEMBL10842235 | 0.71 | CHRNA7 (0.33) | CHRNA7KCNH2 | |
| SCHEMBL5271990 | 0.71 | MEN1 (0.37) | SIGMAR1 | |
| SCHEMBL24637969 | 0.71 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL22969947 | 0.70 | OPRM1 (0.30) | — | |
| SCHEMBL12852095 | 0.70 | OPRM1 (0.30) | — | |
| SCHEMBL9562288 | 0.69 | CHRNA7 (0.36) | CHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530138-A | A PYRROLIZINE DERIVATIVE; EFFECTIVE IN THE TREATMENT OF SENILE DEMENTIA | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0647642-A1 | 1-Azabicyclo(3.3.0)octane derivatives and their use | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1995-04-12 | — | — | EP | disclosed |