Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330011 | 0.92 | — | — | |
| SCHEMBL330009 | 0.92 | — | — | |
| SCHEMBL330308 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL28164672 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL29078952 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| Hydrochloric Acid SCHEMBL28235390 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| Ammonia Solution, Strong SCHEMBL28164671 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL11433892 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL29078950 | 0.90 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL3373326 | 0.83 | MME (0.47) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512467-A | USED IN DIAGNOSIS OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0378224-B1 | Method of detecting small cell carcinoma and use of acylpeptide hydrolase encoding sequences therefor | GEN HOSPITAL CORP (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5268267-A | Using nucleic acid; hybridization | THE GENERAL HOSPITAL CORPORATION (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1990008457-A2 | METHOD OF DETECTING SMALL CELL CARCINOMA AND USE OF ACYL-PEPTIDE HYDROLASE AND CODING SEQUENCES THEREFOR | THE GENERAL HOSPITAL CORPORATION (US) | 1990-08-09 | — | — | WO | disclosed |
| EP-0378224-A2 | Method of detecting small cell carcinoma and use of acylpeptide hydrolase encoding sequences therefor | THE GENERAL HOSPITAL CORPORATION (US) | 1990-07-18 | — | — | EP | disclosed |