SCHEMBL8968296

SCHEMBL8968296

CCC(OC(C)=O)[Si](C)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
GALR3 O60755 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889597 0.87 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL1005332 0.84 TSHR (0.39) TSHRCHRM2CHRM4CHRM1TBXA2R
Methyl Alcohol SCHEMBL28209290 0.83 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL1719176 0.80 TSHR (0.37) TSHRALDH1A1
SCHEMBL15091383 0.78 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL8628389 0.78 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL17138357 0.78 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL6267517 0.77 TSHR (0.36) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL28529148 0.77 TSHR (0.36) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL1603671 0.76 TSHR (0.37) TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520608-B1 Silicones which contain lateral peripheral vinyl ether groups crosslinkable by cationic photoinitiators and their application for coatings and antiadhesive products for paper DOW CORNING (US) 1996-03-06 EP disclosed
US-5486422-A Photo-crosslinkable silicones and their use DOW CORNING CORPORATION (US) 1996-01-23 US disclosed
US-5436309-A Photo-crosslinkable silicones comprising oxyalkylene styrene groups and their use DOW CORNING CORPORATION (US) 1995-07-25 US disclosed
EP-0621302-A1 Photo-crosslinkable silicones and their use DOW CORNING CORPORATION (US) 1994-10-26 EP disclosed
US-5208312-A Release agents DOW CORNING CORPORATION (US) 1993-05-04 US disclosed
EP-0520608-A1 Silicones which contain lateral peripheral vinyl ether groups crosslinkable by cationic photoinitiators and their application for coatings and antiadhesive products for paper DOW CORNING CORPORATION (US) 1992-12-30 EP disclosed