SCHEMBL1005332

SCHEMBL1005332

CCC(OC(C)=O)[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GALR3 O60755 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPV1 Q8NER1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28209290 0.98 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10889597 0.84 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL8968296 0.84 TSHR (0.37) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL524563 0.79 TSHR (0.38) TSHRALDH1A1
SCHEMBL11322949 0.78 HCAR2 (0.38)
SCHEMBL11322959 0.78 HCAR2 (0.38)
SCHEMBL2549996 0.78
SCHEMBL17138350 0.77 TSHR (0.39) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL3226362 0.77 ALDH1A1 (0.43) TSHRALDH1A1LMNAMAPTTDP1
SCHEMBL5308320 0.77 FAAH (0.44) LMNAMAPTTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108059639-B Industrial synthesis method of acetoxypropyl trimethoxy silane 荆州市江汉精细化工有限公司 2020-05-19 CN claimed
CN-108059639-A A kind of industrial preparative method of acetyloxypropyl trimethoxy silane 荆州市江汉精细化工有限公司 2018-05-22 CN claimed
EP-2580294-B1 PVDF COATING COMPOSITIONS SOLVAY SOLEXIS SPA (IT) 2015-02-25 EP claimed
EP-2580294-A1 PVDF COATING COMPOSITIONS Solvay Solexis S.p.A. (IT) 2013-04-17 EP claimed
US-20130090417-A1 PVDF coating compositions SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2013-04-11 US claimed
WO-2011157657-A1 PVDF COATING COMPOSITIONS SOLVAY SOLEXIS S.P.A. (IT) 2011-12-22 WO claimed
EP-3687652-B1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES WATERS TECHNOLOGIES CORP (US) 2025-07-09 EP disclosed
US-20230256413-A1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES WATERS TECHNOLOGIES CORPORATION (US) 2023-08-17 US disclosed
EP-4129466-A1 HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER Waters Technologies Corporation (US) 2023-02-08 EP disclosed
CN-111405934-B Method for isolating, separating, purifying or detecting acidic polar molecules 沃特世科技公司 2022-04-26 CN disclosed
US-20210220753-A1 HIGH PURITY CHROMATROGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER WATERS TECHNOLOGIES CORPORATION (US) 2021-07-22 US disclosed
US-10974167-B2 High purity chromatographic materials comprising an ionizable modifier WATERS TECHNOLOGIES CORPORATION (US) 2021-04-13 US disclosed
CN-112206822-A Composite carrier catalyst for preparing acetoxy propyl alkoxy silane and preparation method thereof 安徽硅宝有机硅新材料有限公司 2021-01-12 CN disclosed
US-20090143606-A1 Production process for a silicon compound JNC CORPORATION (JP) 2009-06-04 US disclosed
US-20090137765-A1 Polymer obtained by addition-polymerization initiated by a silicon compound JNC CORPORATION (JP) 2009-05-28 US disclosed
US-20070004932-A1 Silicon compound and a production process for silicon compound JNC CORPORATION (JP) 2007-01-04 US disclosed
US-20060287454-A1 Silicon compounds JNC CORPORATION (JP) 2006-12-21 US disclosed
US-7129370-B2 Silicon compound and a production process for silicon compound CHISSO CORPORATION (JP) 2006-10-31 US disclosed
US-20050033077-A1 Production process for silicon compound and the same JNC CORPORATION (JP) 2005-02-10 US disclosed
US-4329483-A FROM A CHLOROSILANE AND ACYLOXY COMPOUND; BY-PRODUCT INHIBITION DOW CORNING CORPORATION (US) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143606-A1 Production process for a silicon compound NAF1, H1-0, SPTBN1 TSHR 2393/4885CHRM2 2290/4885CHRM4 2417/4885
US-20070004932-A1 Silicon compound and a production process for silicon compound STS, SMS, SRM TSHR 1330/4885CHRM2 550/4885CHRM4 1724/4885
US-20060287454-A1 Silicon compounds H1-0, SPTBN1, SPTAN1 TSHR 2568/4885CHRM2 2255/4885CHRM4 2658/4885
US-20050033077-A1 Production process for silicon compound and the same STS, SMS, SFXN1 TSHR 1571/4885CHRM2 403/4885CHRM4 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.