SCHEMBL8968381

SCHEMBL8968381

CC(C)CC(COC(=O)CC(O)(CC(=O)O)C(=O)O)CC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CACNA2D1 P54289 2/20 0.35
ADRA1A P35348 2/20 0.35
CACNB3 P54284 1/20 0.35
CACNA1C Q13936 1/20 0.35
PGR P06401 1/20 0.35
HTR2B P41595 1/20 0.35
CACNA2D2 Q9NY47 1/20 0.35
KDM4E B2RXH2 4/20 0.35
LMNA P02545 3/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
PSMB8 P28062 1/20 0.33
PSMB9 P28065 1/20 0.33
PSMB6 P28072 1/20 0.33
PSMB5 P28074 1/20 0.33
PSMB10 P40306 1/20 0.33
SLC13A5 Q86YT5 4/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2829363 0.87 ALDH1A1 (0.54) ALDH1A1ADRA1AKDM4ELMNAMAPT
SCHEMBL23446221 0.86 ALDH1A1 (0.46) ALDH1A1KDM4ELMNAMAPTALOX15
SCHEMBL28488194 0.84 ALDH1A1 (0.50) ALDH1A1ADRA1AKDM4ELMNAMAPT
SCHEMBL425246 0.83 ALDH1A1 (0.54) ALDH1A1ADRA1AKDM4ELMNAMAPT
SCHEMBL489813 0.82 ALDH1A1 (0.52) ALDH1A1ADRA1AKDM4ELMNAMAPT
SCHEMBL5475558 0.81 ALDH1A1 (0.43) ALDH1A1KDM4ELMNAMAPTALOX15
SCHEMBL28497805 0.81 ALDH1A1 (0.50) ALDH1A1ADRA1AKDM4ELMNAMAPT
SCHEMBL536804 0.80 ALDH1A1 (0.42) ALDH1A1KDM4ELMNAMAPTALOX15
SCHEMBL536764 0.79 ALDH1A1 (0.48) ALDH1A1ADRA1AKDM4ELMNAMAPT
SCHEMBL428393 0.79 ALDH1A1 (0.48) ALDH1A1ADRA1AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565595-A REACTION PRODUCTS OF TITANATES WITH BETA-DICARBONYL COMPOUNDS AND CITRATES BAYER AKTIENGESELLSCHAFT (DE) 1996-10-15 US disclosed
US-5428103-A Curable one-component RTV comprising silane crosslinkers, reaction product of titanates, dicarbonyls and citrates, fillers BAYER AKTIENGESELLSCHAFT (DE) 1995-06-27 US disclosed