Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EEF2K | O00418 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968442 | 0.78 | PPARA (0.37) | CXCR2FFAR4CXCR1PLA2G10PLA2G2A | |
| SCHEMBL8417747 | 0.77 | FFAR1 (0.39) | FFAR1PTGDRPTGDR2KDM4EPOLB | |
| SCHEMBL8422012 | 0.75 | PTGDR (0.37) | CXCR2FFAR1CXCR1PTGDRPTGDR2 | |
| SCHEMBL27436177 | 0.74 | PPARA (0.39) | RXRAPTGDRPTGDR2 | |
| SCHEMBL8419815 | 0.74 | POLB (0.50) | FFAR1RXRAPOLBPTGS2 | |
| SCHEMBL8418498 | 0.74 | PTGS2 (0.43) | CXCR2CXCR1PTGDRPTGDR2KDM4E | |
| SCHEMBL4652352 | 0.73 | CXCR2 (0.57) | CXCR2FFAR1FFAR4CXCR1PLA2G10 | |
| SCHEMBL8418567 | 0.72 | AKR1C3 (0.36) | KDM4ES1PR1 | |
| SCHEMBL8421517 | 0.72 | PTGDR (0.48) | FFAR1PTGDRPTGDR2KDM4E | |
| SCHEMBL27437226 | 0.71 | ELANE (0.40) | CXCR2CXCR1PTGDRPTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |