SCHEMBL8968472

SCHEMBL8968472

NC1CCCCCCC=CCCCCCCC1

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL570505 1.00 THRB (0.35) THRBMEN1KMT2AALDH1A1
SCHEMBL8968469 1.00 THRB (0.35) THRBMEN1KMT2AALDH1A1
SCHEMBL21310709 0.95 THRB (0.32) THRBMEN1KMT2AALDH1A1
SCHEMBL21466017 0.95 THRB (0.32) THRBMEN1KMT2AALDH1A1
SCHEMBL13357074 0.87 THRB (0.30) THRBMEN1KMT2AALDH1A1
SCHEMBL21261786 0.83
SCHEMBL19445459 0.83
SCHEMBL1536157 0.82
SCHEMBL1536155 0.82
SCHEMBL17992603 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451822-B1 Use of macrocyclic compounds as components for ferroelectric liquid crystal mixtures HOECHST AG (DE) 1996-02-14 EP disclosed
US-5178792-A Electrooptical appartus with improved contrast HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-12 US disclosed
EP-0451822-A2 Use of macrocyclic compounds as components for ferroelectric liquid crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-16 EP disclosed