Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967825 | 0.82 | HAO1 (0.46) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| Hydrochloric Acid SCHEMBL8968011 | 0.81 | HAO1 (0.45) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| Hydrochloric Acid SCHEMBL8968395 | 0.79 | MAOA (0.43) | ALDH1A1MAOAMAOBHTTPTPN1 | |
| SCHEMBL9383438 | 0.76 | MAOA (0.46) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL8967945 | 0.76 | MAOA (0.49) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL9537636 | 0.76 | HAO1 (0.47) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL9384006 | 0.75 | HTT (0.45) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL8968574 | 0.75 | MAOA (0.44) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| Hydrochloric Acid SCHEMBL8967902 | 0.74 | HAO1 (0.46) | ALDH1A1CYP1A2CYP2D6MAOAMAOB | |
| SCHEMBL3890165 | 0.74 | HTT (0.50) | ALDH1A1CYP1A2CYP2D6MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504095-A | Aminobenzosultam derivatives as lipoxygenase inhibitors | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0549666-B1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0549666-A1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS. | PFIZER (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992005164-A1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1992-04-02 | — | — | WO | disclosed |