Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312970 | 0.95 | GSK3B (0.41) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL11015946 | 0.90 | GSK3B (0.45) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL11206986 | 0.90 | GSK3B (0.45) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL10712855 | 0.90 | GSK3B (0.45) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL10914947 | 0.90 | GSK3B (0.45) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL10354541 | 0.88 | GSK3B (0.43) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL5970012 | 0.84 | GSK3B (0.50) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL1234203 | 0.84 | GSK3B (0.39) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL2508510 | 0.84 | NR1H2 (0.47) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7403092 | 0.84 | KDM4E (0.42) | PARP1GSK3BKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374908-A | Foamed and foamable high glass transition temperature polymers | GEN ELECTRIC (US) | 2009-02-25 | — | — | CN | claimed |
| CN-101370873-A | Annular or tubular shaped articles of novel polymer blends | GEN ELECTRIC (US) | 2009-02-18 | — | — | CN | claimed |
| CN-101370872-A | Food service articles of manufacture comprising high temperature polymers | GEN ELECTRIC (US) | 2009-02-18 | — | — | CN | claimed |
| CN-101351506-A | High glass transition temperature thermoplastic articles | GEN ELECTRIC (US) | 2009-01-21 | — | — | CN | claimed |
| CN-1871280-A | Phase transfer catalytic process for the preparation of polyetherimides | GEN ELECTRIC (US) | 2006-11-29 | — | — | CN | claimed |
| CN-1867610-A | Copolyetherimides | GEN ELECTRIC (US) | 2006-11-22 | — | — | CN | claimed |
| CN-1871280-A | Phase transfer catalytic process for the preparation of polyetherimides | GEN ELECTRIC (US) | 2006-11-29 | — | — | CN | disclosed |
| CN-1867610-A | Copolyetherimides | GEN ELECTRIC (US) | 2006-11-22 | — | — | CN | disclosed |
| US-5585392-A | TREATING OR PREVENTING STROKES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5506246-A | Method for treating depression using substituted aminomethyltetralins and their heterocyclic analogues | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |
| US-5463105-A | Therapy for cardiovascular, nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0352613-B1 | Substituted amino methyl tetralines, and their heterocyclic analogous compounds | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-5298513-A | Serotonin antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | disclosed |
| US-5021438-A | Having affinity for 5-hydroxytryptamine receptors; treating central nervous system and cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0390515-A1 | Novel adenine derivatives and their use as agents for increasing crop yields | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-10-03 | — | — | EP | disclosed |
| EP-0352613-A2 | Substituted amino methyl tetralines, and their heterocyclic analogous compounds | BAYER AG (DE) | 1990-01-31 | — | — | EP | disclosed |
| US-4880802-A | CENTRAL NERVOUS SYSTEM | BAYER AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | disclosed |
| EP-0332968-A1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |
| EP-0270947-A2 | Substituted basic 2-aminotetralines | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| US-3965125-A | Synthesis of certain bis(phthalic anhydrides) | TRW INC. (US) | 1976-06-22 | — | — | US | disclosed |