Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31197078 | 0.95 | ACHE (0.68) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968183 | 0.95 | ACHE (0.68) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8970192 | 0.94 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969338 | 0.81 | ACHE (0.89) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969782 | 0.77 | ACHE (0.56) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969241 | 0.77 | ACHE (0.97) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968520 | 0.77 | ACHE (0.68) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968767 | 0.77 | ACHE (0.68) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969574 | 0.77 | ACHE (0.63) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969841 | 0.77 | ACHE (0.63) | ACHEBCHEMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |