Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969007 | 0.81 | POLB (0.33) | TSHRPOLBNPSR1 | |
| SCHEMBL4263557 | 0.78 | CHRM2 (0.34) | TSHR | |
| SCHEMBL8969972 | 0.78 | CHRM2 (0.34) | TSHR | |
| SCHEMBL29411787 | 0.77 | TSHR (0.40) | TSHRPOLBNPSR1 | |
| SCHEMBL8969290 | 0.77 | TSHR (0.35) | TSHR | |
| SCHEMBL10121177 | 0.74 | TSHR (0.46) | TSHRPOLBNPSR1 | |
| SCHEMBL1297587 | 0.74 | TSHR (0.46) | TSHRPOLBNPSR1 | |
| SCHEMBL8970005 | 0.73 | MAPK1 (0.33) | — | |
| SCHEMBL8970421 | 0.73 | CYP1A2 (0.36) | TSHR | |
| SCHEMBL8969484 | 0.71 | ALOX15 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |