SCHEMBL896931

SCHEMBL896931

COC(=O)c1ccccc1C(=O)OCCO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.65
ALDH1A1 P00352 6/20 0.61
TDP1 Q9NUW8 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
CYP3A4 P08684 2/20 0.56
MAPK1 P28482 2/20 0.56
TP53 P04637 1/20 0.56
KDM4E B2RXH2 2/20 0.56
GLA P06280 1/20 0.56
LMNA P02545 3/20 0.54
CFTR P13569 1/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 1/20 0.50
ATM Q13315 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36533 0.90 ALDH1A1 (0.67) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL873755 0.89 TSHR (0.64) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL30749815 0.88 ALDH1A1 (0.64) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL18668786 0.88 TSHR (0.65) TSHRALDH1A1TDP1L3MBTL1CYP3A4
Dimethyl Phthalate SCHEMBL28724515 0.87 KDM4E (0.57) TSHRALDH1A1KDM4EGLALMNA
SCHEMBL22225761 0.86 TSHR (0.53) TSHRALDH1A1TDP1L3MBTL1CYP3A4
Dimethyl Phthalate SCHEMBL81887 0.86 KDM4E (0.65) TSHRALDH1A1KDM4EGLALMNA
SCHEMBL18411634 0.85 ALDH1A1 (0.61) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL12377229 0.85 TSHR (0.89) TSHRALDH1A1TDP1L3MBTL1CYP3A4
Dimethyl Phthalate SCHEMBL11138523 0.85 KDM4E (0.56) TSHRALDH1A1KDM4EGLALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112353905-A Traditional Chinese medicine formula for promoting sleep 珠海琴健中医药科技有限公司 2021-02-12 CN disclosed
CN-106729328-A A kind of Chinese medicine composition for the treatment of cancer and its application 王政和 2017-05-31 CN disclosed
CN-106459471-A Recycling method of mixed PET plastic product 卡比欧斯公司 2017-02-22 CN disclosed
EP-2105795-B1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORP (JP) 2016-12-28 EP disclosed
US-9250356-B2 Photochromic polymers VIVIMED LABS EUROPE LTD (GB) 2016-02-02 US disclosed
EP-2085220-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2015-05-20 EP disclosed
US-8992668-B2 Gas separation membrane and method for producing the same, and method for separating gas mixture, gas separation membrane module and gas separation apparatus using the same FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8747521-B2 Gas separation membrane and method for producing the same, and gas separating method, module and separation apparatus using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8669040-B2 Method of manufacturing relief printing plate and printing plate precursor for laser engraving FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
US-20090191481-A1 Method of manufacturing relief printing plate and printing plate precursor for laser engraving FUJIFILM CORPORATION (JP) 2009-07-30 US disclosed
EP-2082874-A1 Method of manufacturing relief printing plate and printing plate precursor for laser engraving Fujifilm Corporation (JP) 2009-07-29 EP disclosed
US-20090123712-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD FOR PRODUCTION OF RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
EP-2058123-A2 Resin composition for laser engraving, resin printing plate precursor for laser engraving, relief printing plate and method for production of relief printing plate FUJIFILM Corporation (JP) 2009-05-13 EP disclosed
EP-2047987-A2 Resin composition for laser engraving, resin printing plate precursor for laser engraving, relief printing plate and method for production of relief printing plate FUJIFILM Corporation (JP) 2009-04-15 EP disclosed
US-20090081414-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD FOR PRODUCTION OF RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-4801632-A Cellulose ester moulding materials with improved toughness BAYER AKTEINGESELLSCHAFT (DE) 1989-01-31 US disclosed
US-4427809-A Thermoplastic moulding compositions of co-graft polymers BAYER AKTIENGESELLSCHAFT (DE) 1984-01-24 US disclosed
US-4360635-A Thermoplastic moulding compositions of cellulose ester graft copolymers or mixtures thereof with cellulose esters BAYER AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
US-4357267-A ETHYLENE-VINYL ESTER COPOLYMER BAYER AKTIENGESELLSCHAFT (DE) 1982-11-02 US disclosed