Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MMP9 | P14780 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 16/20 | 0.37 |
| ▸ | CA2 | P00918 | 16/20 | 0.37 |
| ▸ | CA9 | Q16790 | 15/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA7 | P43166 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.36 |
| ▸ | CA3 | P07451 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA6 | P23280 | 4/20 | 0.36 |
| ▸ | CA5A | P35218 | 4/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10787503 | 0.98 | TSHR (0.65) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL2057502 | 0.93 | USP2 (0.64) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL2058014 | 0.83 | USP2 (0.55) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL4764696 | 0.83 | TSHR (1.00) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL4373 | 0.83 | TSHR (1.00) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL4298840 | 0.80 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL7195165 | 0.80 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL8592211 | 0.80 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL1335477 | 0.80 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL4952202 | 0.80 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536732-A | REDUCING INFECTIOUSNESS OF HIV | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0454580-B1 | Novel nojirimycin derivatives | MERRELL DOW PHARMA (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5252587-A | Viricides, aids therapy, antidiabetic agent | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0454580-A2 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0453692-A1 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |