Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19545885 | 0.85 | CYP2C9 (0.76) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL18417198 | 0.83 | TSHR (0.58) | CYP2C9TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL27804511 | 0.82 | CYP2C9 (0.49) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL12012109 | 0.81 | TSHR (0.56) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL17034727 | 0.81 | CYP2C9 (0.55) | CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL6220376 | 0.81 | CYP2C9 (0.47) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL8419721 | 0.79 | LDHA (0.42) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL2014212 | 0.79 | KMT2A (0.47) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL19944241 | 0.78 | CYP2C9 (0.78) | CYP2C9TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL20898870 | 0.78 | MAPT (0.59) | TSHRALDH1A1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |