SCHEMBL8969495

SCHEMBL8969495

CCCOC1CCCCCCC1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.38
PTPN1 P18031 1/20 0.38
PPP1CC P36873 1/20 0.38
PPP5C P53041 1/20 0.38
PEPD P12955 1/20 0.34
GRM2 Q14416 1/20 0.34
GRM3 Q14832 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970379 1.00 PPM1B (0.38) PPM1BPTPN1PPP1CCPPP5CPEPD
SCHEMBL8970440 0.98 PPM1B (0.39) PPM1BPTPN1PPP1CCPPP5CPEPD
SCHEMBL8970745 0.95 PPM1B (0.39) PPM1BPTPN1PPP1CCPPP5CPEPD
SCHEMBL8969601 0.90 PPP5C (0.49) PPP5C
SCHEMBL8970033 0.90 PPP5C (0.49) PPP5C
SCHEMBL8970439 0.88 PPP5C (0.44) PPP5C
SCHEMBL8970248 0.88 PPP5C (0.44) PPP5C
SCHEMBL10435067 0.88 PPP5C (0.50) PPP5C
SCHEMBL8970054 0.88 PPP5C (0.50) PPP5C
SCHEMBL8970214 0.87 PPP5C (0.43) PPP5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed