SCHEMBL8970745

SCHEMBL8970745

CCCOC1CCCC1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.39
PTPN1 P18031 1/20 0.39
PPP1CC P36873 1/20 0.39
PEPD P12955 1/20 0.39
PPP5C P53041 1/20 0.39
ACE P12821 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970440 0.96 PPM1B (0.39) PPM1BPTPN1PPP1CCPEPDPPP5C
SCHEMBL8970379 0.95 PPM1B (0.38) PPM1BPTPN1PPP1CCPEPDPPP5C
SCHEMBL8969495 0.95 PPM1B (0.38) PPM1BPTPN1PPP1CCPEPDPPP5C
SCHEMBL8971152 0.89 PPP5C (0.50) PPM1BPTPN1PPP1CCPEPDPPP5C
SCHEMBL8970893 0.89 PPP5C (0.50) PPM1BPTPN1PPP1CCPEPDPPP5C
SCHEMBL8969547 0.88 PPP5C (0.46) PEPDPPP5C
Hydrochloric Acid SCHEMBL8970289 0.88 PPP5C (0.49) PPM1BPTPN1PPP1CCPEPDPPP5C
SCHEMBL8969992 0.86 PPP5C (0.44) PPP5C
SCHEMBL8970321 0.86 PPP5C (0.44) PPP5C
SCHEMBL8970562 0.86 PPP5C (0.44) PPP5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168367-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-09-07 WO disclosed
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed