Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584039 | 0.95 | MAPK1 (0.46) | KDM4EMAPK1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL670276 | 0.95 | MAPK1 (0.46) | KDM4EMAPK1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL6089644 | 0.88 | APP (0.41) | TSHRKDM4EMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL16668774 | 0.87 | TSHR (0.55) | TSHRKDM4EMAPK1ALDH1A1TDP1 | |
| SCHEMBL13846053 | 0.86 | CYP1A2 (0.53) | TSHRKDM4EMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL10048853 | 0.86 | CYP1A2 (0.53) | KDM4EMAPK1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13845920 | 0.84 | CYP1A2 (0.51) | TSHRKDM4EMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL22297588 | 0.82 | KDM4E (0.52) | TSHRKDM4EMAPK1ALDH1A1TDP1 | |
| SCHEMBL15723552 | 0.81 | MAPK1 (0.58) | TSHRKDM4EMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL14972871 | 0.81 | MAPK1 (0.61) | TSHRKDM4EMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492687-A | X-RAY CONTRAST AGENTS | STERLING WINTHROP INC. (US) | 1996-02-20 | — | — | US | claimed |
| US-5466435-A | X-ray contrast agents, radiology | STERLING WINTHROP INC. (US) | 1995-11-14 | — | — | US | claimed |
| US-5348727-A | Diagnostics | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | claimed |
| US-5310538-A | Contrast agents | STERLING WINTHROP INC. (US) | 1994-05-10 | — | — | US | claimed |
| EP-0746339-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING AS (NO) | 1996-12-11 | — | — | EP | disclosed |
| US-5492687-A | X-RAY CONTRAST AGENTS | STERLING WINTHROP INC. (US) | 1996-02-20 | — | — | US | disclosed |
| US-5466435-A | X-ray contrast agents, radiology | STERLING WINTHROP INC. (US) | 1995-11-14 | — | — | US | disclosed |
| WO-1995022995-A1 | X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES | NYCOMED IMAGING A/S (NO) | 1995-08-31 | — | — | WO | disclosed |
| EP-0619121-A2 | Compositions of iodophenoxy alkylene ethers for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-10-12 | — | — | EP | disclosed |
| US-5348727-A | Diagnostics | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0614670-A2 | Compositions of iodophenoxy alkylene ethers in film-formin materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-09-14 | — | — | EP | disclosed |
| US-5310538-A | Contrast agents | STERLING WINTHROP INC. (US) | 1994-05-10 | — | — | US | disclosed |