Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969302 | 0.99 | ACHE (0.50) | ACHEMAOABCHEPDE3BPDE3A | |
| SCHEMBL8969539 | 0.83 | ACHE (0.43) | ACHE | |
| SCHEMBL8969525 | 0.82 | ACHE (0.45) | ACHEMAOABCHELMNAMEN1 | |
| SCHEMBL8969694 | 0.81 | ACHE (0.46) | ACHEMAOABCHELMNAMEN1 | |
| SCHEMBL8968558 | 0.78 | ACHE (0.48) | ACHEMAOABCHELMNAMEN1 | |
| SCHEMBL8969163 | 0.77 | ACHE (0.50) | ACHEMAOABCHELMNAMEN1 | |
| SCHEMBL8969195 | 0.76 | ACHE (0.54) | ACHEBCHEPDE3BPDE3ALMNA | |
| SCHEMBL8968961 | 0.75 | ACHE (0.60) | ACHEBCHEPDE3BPDE3ALMNA | |
| SCHEMBL8969663 | 0.75 | ACHE (0.56) | ACHEBCHEPDE3BPDE3ALMNA | |
| SCHEMBL8969687 | 0.74 | ACHE (0.68) | ACHEBCHEPDE3BPDE3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |