SCHEMBL8969682

SCHEMBL8969682

COc1ccccc1NCCCCS(=O)(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.63
GBA1 P04062 1/20 0.43
RAD52 P43351 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA1D P25100 1/20 0.43
ADRA1A P35348 1/20 0.43
ADRA1B P35368 1/20 0.43
HDAC3 O15379 2/20 0.42
HDAC4 P56524 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC7 Q8WUI4 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC10 Q969S8 2/20 0.42
HDAC11 Q96DB2 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
HDAC9 Q9UKV0 2/20 0.42
HDAC5 Q9UQL6 2/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8969112 0.97 CHRM2 (0.64) CHRM2GBA1RAD52HTR1AADRA1D
SCHEMBL11147544 0.97 CHRM2 (0.63) CHRM2GBA1RAD52HTR1AADRA1D
SCHEMBL10800208 0.91 CHRM2 (0.58) CHRM2HDAC3HDAC4HDAC1HDAC7
SCHEMBL24277324 0.87 CHRM2 (0.48) CHRM2HTR1AADRA1DADRA1AADRA1B
SCHEMBL24277459 0.84 CHRM2 (0.48) CHRM2HTR1AADRA1DADRA1AADRA1B
SCHEMBL8969103 0.84 CHRM2 (0.62) CHRM2HTR1AADRA1DADRA1AADRA1B
SCHEMBL6259329 0.82 CHRM2 (0.46) CHRM2GBA1HTR1AADRA1DADRA1A
Sulfuric Acid SCHEMBL4244724 0.81 CHRM2 (0.58) CHRM2GBA1RAD52HDAC3HDAC4
SCHEMBL28182344 0.81 CHRM2 (0.45) CHRM2GBA1HTR1AADRA1DADRA1A
SCHEMBL2914972 0.81 CHRM2 (0.53) CHRM2KMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510532-A ANILINE DERIVATIVES CONTAINING ALKYLSULFONATE GROUP ON NITROGEN ATOM KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-04-23 US disclosed
US-5500474-A POLYANILINE SULFONATES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-03-19 US disclosed