Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073595 | 0.92 | CHRM2 (0.62) | CHRM2KDM4EGLAGBA1USP2 | |
| Sulfuric Acid SCHEMBL7104162 | 0.85 | KDM4E (0.46) | CHRM2KDM4EGLAGBA1USP2 | |
| SCHEMBL10800208 | 0.84 | CHRM2 (0.58) | CHRM2KDM4EALDH1A1HDAC3HDAC4 | |
| Sulfuric Acid SCHEMBL4593175 | 0.83 | CHRM2 (0.53) | CHRM2ALDH1A1MEN1KMT2A | |
| SCHEMBL11109142 | 0.81 | CHRM2 (0.68) | CHRM2KDM4EGLAGBA1USP2 | |
| SCHEMBL11147544 | 0.81 | CHRM2 (0.63) | CHRM2GBA1RAD52ALDH1A1HDAC3 | |
| SCHEMBL8969682 | 0.81 | CHRM2 (0.63) | CHRM2GBA1RAD52ALDH1A1HDAC3 | |
| SCHEMBL2914972 | 0.80 | CHRM2 (0.53) | CHRM2HTTALDH1A1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL9680698 | 0.79 | GAA (0.43) | CHRM2KDM4EGLATSHRHTT | |
| SCHEMBL8969112 | 0.79 | CHRM2 (0.64) | CHRM2GBA1RAD52HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10064471-B2 | Air oxidation hair dye application system and method for coloring hair using the same | COMBE INCORPORATED (US) | 2018-09-04 | — | — | US | disclosed |
| CN-106280828-A | A kind of elastic water proofing paint | 四川力久云智知识产权运营有限公司 | 2017-01-04 | — | — | CN | disclosed |
| US-9532937-B2 | Hair treatment methods and kits thereof | NOXELL CORPORATION (US) | 2017-01-03 | — | — | US | disclosed |
| US-9468278-B2 | Hair colouring methods and kits thereof | THE PROCTER & GAMBLE COMPANY (US) | 2016-10-18 | — | — | US | disclosed |
| CN-104151178-B | 2-amino-4-(beta-hydroxyethyl amino) methyl phenyl ethers anisole and the preparation method of sulfate thereof | 江苏鼎龙科技有限公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-3041904-A1 | STYRYL SULFIDE DYES | BASF SE (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-9339451-B2 | Hair colouring methods and kits thereof | THE PROCTER & GAMBLE COMPANY (US) | 2016-05-17 | — | — | US | disclosed |
| WO-2015028543-A1 | STYRYL SULFIDE DYES | BASF SE (DE) | 2015-03-05 | — | — | WO | disclosed |
| US-20150053229-A1 | Hair Colouring Methods and Kits Thereof | WELLA OPERATIONS US, LLC | 2015-02-26 | — | — | US | disclosed |
| US-20150053228-A1 | Hair Colouring Methods and Kits Thereof | WELLA OPERATIONS US, LLC | 2015-02-26 | — | — | US | disclosed |
| WO-2015026991-A2 | HAIR COLOURING METHODS AND KITS THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20150053226-A1 | Hair Treatment Methods and Kits Thereof | WELLA OPERATIONS US, LLC | 2015-02-26 | — | — | US | disclosed |
| US-20090114237-A1 | AIR OXIDATION HAIR DYE APPLICATION SYSTEM AND METHOD FOR COLORING HAIR USING THE SAME | COMBE INCORPORATED (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150053228-A1 | Hair Colouring Methods and Kits Thereof | COXFA4L2, ALPG, NACA | CHRM2 4865/4885KDM4E 2410/4885GLA 271/4885 |
| US-20150053229-A1 | Hair Colouring Methods and Kits Thereof | SHH, NACA, TES | CHRM2 4851/4885KDM4E 2827/4885GLA 591/4885 |
| US-20150053226-A1 | Hair Treatment Methods and Kits Thereof | SUCLG1, COXFA4L2, TYR | CHRM2 4881/4885KDM4E 1699/4885GLA 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.